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2. A patient was receiving 2 tablets of dillutane, 10 mg orally, and 1 tablet of clonidine, 80 mg orally, as adjunctive therapy for a lumbar spinal disc herniation. The doses
lisinopril-hydrochlorothiazide 10-12.5 mg oral tablet exceeded recommended maximum dose, and the dosage was not indicated. Clonidine is labeled for use in patients age 18 and older only.
3. A 34-year-old woman was admitted to the ICU after developing a seizure associated with dysuria and fever developed hypotension after receiving clonidine monotherapy up to 2000 mg/24 h. The temperature was 38.0°C when she began clonidine treatment of 9.6 mg orally at 0800. After a decrease in the oral dosing from 9.6 to 9.1 mg, the temperature fell to 35.5°C with a drop in the urinary pH to 8.5. patient had no recent use of an opioid, nor was she taking a diuretic. The patient's BP was 110/80 (systolic) and 89/57 (diastolic), her serum bicarbonate was 9 mm Hg. She receiving a single bolus of 6-chlorothiazide 12 mg.
4. A 63-year-old woman was admitted to the ICU after developing a worsening fever, dysuria, and hypotension due to diuretic use. She was receiving clonidine monotherapy of 10 mg orally at 0800. The temperature was 38.0°C when she began clonidine therapy of 6 mg orally at 0800. After a decrease in the oral dosing from 10 to 6 mg, the temperature fell to 35.5°C with a decline of the urinary pH to 8.6. She had consumed a large amount of carbonated water but no diuretic and had recent prescription opioids.
A 4-year-old boy entered the ICU in late afternoon and developed respiratory distress. The temperature was 38°C and he receiving oral clonidine, as directed. The temperature was not reported to have been changed while he was at the hospital since his admission. On laboratory, he received 4 doses of clonidine monotherapy 5, and 10 mg given intravenously at 0800 and 2100 0744; his temperature was 38°C, serum BUN 4.73, his pH was 7.00, and urine BUN 2.23.
CONCLUSION:
Clonidine monotherapy leads to increased risk of hypotension. These risks are independent of long-term treatment with clonidine. What do we make of the US
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I'm sorry, but most "socialized medicine" initiatives in the US have nothing to do with addressing a shortage of health-care providers, and have little to do with providing healthcare, but rather, is mostly about using health as a means to benefit small but politically-connected elite.
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Other medications may interact with phenytoin, including prescription, non-prescription, and over-the-counter medications. When using phenytoin, it is important to inform your doctor about all other medications you use, including vitamins and herbs. Not all individuals respond to treatment with phenytoin. Your doctor or pharmacist will decide which treatment is right for you.
Warnings
Phenytoin may diminish the effects of phenobarbital and should not be used together with this medication.
Phenytoin may increase the effects of phenytoin in some patients. This has been reported in a few cases.
Phenytoin side effects
Get emergency medical help if you have signs of an allergic reaction to phenytoin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking phenytoin and contact your doctor at once if you have:
sudden unexpected weight gain (especially in patients who weigh more than 200 pounds or more);
a seizure (convulsions);
a severe headache;
a sharp or pounding headache;
nausea, loss of appetite, burning in your mouth, stomach pain;
trouble sleeping;
sudden trouble speaking, attention deficit or hyperactivity problems;
confusion, problems with thinking;
shakiness, restlessness; or
unusual mood or behavior changes (fear, agitation, hallucinations, hostility).
Common phenytoin side effects may include:
constipation;
trouble swallowing;
changes in your appetite;
weight gain, feeling hungry after meals;
dry mouth;
changes in your menstrual periods (menstrual after starting phenytoin may be more severe or less regular than normal);
increased fluid in your lungs (also known as asthma).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Phenytoin dosing information
Usual Adult Dose for Obesity:
Initial dose:
2 mg orally once daily
Maintenance dose:
1.5 mg orally once daily
Maximum dose:
3 mg orally once daily
Comments:
-Treatment should normally be initiated at 2 mg orally once daily, then maintained at this dose for 5 days. The maximum daily dose should then be reduced gradually (daily maintenance dose by 50% of initial dose) for another 5 to 7 days. Dose reductions in advance of the planned decrease may not have the therapeutic effect.
-If abrupt weight online pharmacy oxycodone 30mg gain occurs, then loss or diet changes may be initiated. Weight loss should supervised.
This is not a complete list of dose adjustments and other Comments:
-Treatment should normally be initiated at 2 mg orally once daily, then maintained at this dose for 5 days.
-The maximum dose should then be reduced gradually by 50% (daily maintenance dose of initial dose) for another 5 to 7 days.
-Treatment should generally not be interrupted unless indicated to achieve treatment goals.
This is not a complete list of weight loss side effects and other Comments:
-The maximum daily dose should then be Lisinopril 10mg $280.99 - $0.78 Per pill reduced gradually by 50% (daily maintenance dose of initial dose) for another 5 to 7 days.
Usual Adult Dose for High Blood Pressure:
2-5 mg orally once daily
5 mg orally once daily
Usual Pediatric Dose for Obesity:
0.25 mg orally every 12 hours, by mouth
1.0 mg orally every 12 hours, by mouth
2.0 mg orally once per day
-Administration should generally begin at 0.25 mg orally once per hour, and gradually increase to 4 mg orally once every 12 hours, by mouth.
-Adjunctive therapy with a diuretic at maintenance dose does not appear to reduce the overall efficacy of antihyperglycemic agent.
-In patients with a history of sudden or excessive acceleration blood pressure [see WARNINGS], the initial dose should be adjusted by 50% after 1.
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